What Is Clostridium Difficile (C. Difficile)?

Clostridium difficile, also known as C. difficile, or C. diff, is a bacterium which infects and can make humans ill, as well as other animals. Symptoms can range from diarrhea to serious and potentially fatal inflammation of the colon. Elderly hospital patients, as well as those in long-term care facilities are most commonly affected by C.